PV/PMS is saddled with the following responsibilities;

• Implementation of National Policy on Pharmacovigilance and provision of science-based advice and information on safe use of medicines.
• Post Marketing Surveillance of all Regulated Products in collaboration with Marketing Authorization Holders (MAHs).
• Coordination of Pharmacovigilance activities Nationwide.
• Implementation of Risk Management Plans (RMP) in collaboration with the Pharmaceutical Industry and MAHs as appropriate
• Pharmacovigilance Inspections.
• Supporting the establishment of active Pharmacovigilance Centers in Healthcare Institutions in the Country.
• Creation of awareness on Pharmacovigilance among health professionals, healthcare providers, Marketing Authorization Holders and the general public.
• Promoting rational and safe use of medicines in Nigeria.
• Medicine safety communication.
• Coordinating the activities of the National Drug Safety Advisory Committee (NDSAC).
• Sourcing, collating, preserving, storing, retrieving and dissemination of information on food, drugs, cosmetics, Chemicals, and other NAFDAC regulated products.
• Establishing and maintaining a functional national database on ADRs and other medicine related problems.
• Conducting regular survey on regulated products for required regulatory action.
• Coordinating the activities of NAFDAC Consumer Safety Club NCSC in Secondary Schools and NAFDAC Consumer Safety Publications NCSP.